NOC:Principles and Applications of NMR Spectroscopy (USB)

Media Storage Type : 32 GB USB Stick

NPTEL Subject Matter Expert : Prof. Hanudatta S. Atreya

NPTEL Co-ordinating Institute : IISc Bangalore

NPTEL Lecture Count : 40

NPTEL Course Size : 11 GB

NPTEL PDF Text Transcription : Available and Included

NPTEL Subtitle Transcription : Available and Included (SRT)

Lecture Titles:

Lecture 1 - Introduction to NMR spectroscopy
Lecture 2 - The alignment of nuclear spins in presence of magnetic field
Lecture 3 - Introduction to rotating frame
Lecture 4 - Free induction decay and Fourier transformation of FID
Lecture 5 - NMR Hardware
Lecture 6 - The concept of chemical shift
Lecture 7 - Factors that affect chemical shifts
Lecture 8 - Chemical shift referencing
Lecture 9 - J-coupling
Lecture 10 - Recap of basics
Lecture 11 - Introduction to general one dimensional NMR experiment
Lecture 12 - Practical aspects of recording a 1D NMR experiment - I
Lecture 13 - Practical aspects of recording a 1D NMR experiment - II
Lecture 14 - Practical aspects of recording a 1D NMR experiment - III
Lecture 15 - NMR Data processing
Lecture 16 - Basic aspects of 1D proton NMR analysis
Lecture 17 - Analysis of an example 1D proton spectrum
Lecture 18 - Analysis of 1D 1H NMR spectra of molecules - I
Lecture 19 - Analysis of 1D 1H NMR spectra of molecules - II
Lecture 20 - 1D 13C NMR
Lecture 21 - Why do we need 2D NMR
Lecture 22 - A qualitative explanation of how 2D NMR experiment works
Lecture 23 - Principles of 2D COSY and Total correlation spectroscopy (2D TOCSY)
Lecture 24 - 2D NOE-spectroscopy
Lecture 25 - 2D NOESY and 2D ROESY
Lecture 26 - What is heteronuclear correlation NMR spectroscopy
Lecture 27 - Sensitivity enhancement of heternuclei via polarization transfer
Lecture 28 - Heteronucler multiple quantum NMR spectroscopy (2D HMQC) and Heteronuclear single quantum NMR spectroscopy (2D HSQC)
Lecture 29 - Practical aspects of recording and processing 2D HMQC or HSQC
Lecture 30 - HMBC and its utility
Lecture 31 - 2D HSQC TOCSY and its analysis with examples
Lecture 32 - Structure determination of molecules by NMR
Lecture 33 - Structure determination of peptides - I
Lecture 34 - Structure determination of peptides - II
Lecture 35 - Structure determination of peptides - III
Lecture 36 - Chemical exchange
Lecture 37 - Hydrogen or deuterium exchange
Lecture 38 - Diffusion ordered spectroscopy DOSY I
Lecture 39 - DOSY II
Lecture 40 - STD NMR for drug target interactions