NOC:Principles and Applications of Enolate Alkylation

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Media Storage Type : 32 GB USB Stick

NPTEL Subject Matter Expert : Prof. Samik Nanda

NPTEL Co-ordinating Institute : IIT Kharagpur

NPTEL Lecture Count : 40

NPTEL Course Size : 3.5 GB

NPTEL PDF Text Transcription : Available and Included

NPTEL Subtitle Transcription : Available and Included (SRT)


Lecture Titles:

Lecture 1 - Enolate generation, structure of enolates and related topic - I
Lecture 2 - Enolate generation, structure of enolates and related topic - II
Lecture 3 - Enolate generation, structure of enolates and related topic - III
Lecture 4 - Different mode of asymmetric induction in enolate alkylation
Lecture 5 - Revisit again, Different mode of asymmetric induction in enolate alkylation
Lecture 6 - Substrate directed stereocontrol in acyclic and cyclic system
Lecture 7 - Substrate directed enolate alkylation in bicyclic system
Lecture 8 - Seebachâ's SRS principle and related systems - I
Lecture 9 - Seebachâ's SRS principle and related systems - II
Lecture 10 - Seebachâ's SRS principle and related systems - III
Lecture 11 - Evans oxazolidinone and related systems - I
Lecture 12 - Evans oxazolidinone and related systems - II
Lecture 13 - Evans oxazolidinone and related systems - III
Lecture 14 - Evans oxazolidinone and related systems - IV
Lecture 15 - Evans oxazolidinone and related systems - V
Lecture 16 - Helmchenâ's auxiliary, Oppolzerâ's sultam based auxiliary
Lecture 17 - Camphor based N-acyloxazolidinones as chiral auxiliary
Lecture 18 - Myerâ's ephedrine, Chiral Weinreb amide equivalents and related systems
Lecture 19 - Myerâ's ephedrine and related systems
Lecture 20 - Chiral Weinreb amide equivalents and related systems
Lecture 21 - Meyerâ's oxazoline based alkylation - I
Lecture 22 - Meyerâ's oxazoline based alkylation - II
Lecture 23 - Meyerâ's bicyclic lactam based enolate alkylation
Lecture 24 - Meyerâ's bicyclic lactam based alkylation
Lecture 25 - Meyerâ's bicyclic lactams, Gleasonâ's bicyclic thioglycolate lactam based systems
Lecture 26 - Few problem solving from Meyerâ's oxazoline/bicyclic lactam based alkylation
Lecture 27 - Schollkopfâ's bis-lactim ether and related systems; Auxiliary induced chiral relay
Lecture 28 - Chiral relay systems in amino acid derived enolate alkylation
Lecture 29 - Wiliams oxazinone, Yamada's chiral glycine enolate and related system
Lecture 30 - Tricycloiminolactone as chiral glycine equivalents
Lecture 31 - Najera's auxiliary, Davies diketopoperazine and related system
Lecture 32 - Enderâ's RAMP/SAMP,Coltartâ's cyclic carbamate hydrazone,Ellmanâ's sulfinamide and related
Lecture 33 - Enderâ's RAMP/SAMP based systems
Lecture 34 - Enderâ's RAMP/SAMP based systems
Lecture 35 - Enderâ's RAMP/SAMP, Coltartâ's cyclic carbamate hydrazone,Ellmanâ's sulfinamide
Lecture 36 - Coltartâ's cyclic carbamate hydrazone and its exploration
Lecture 37 - Memory of chirality in enolate alkylation
Lecture 38 - Organocatalytic methods for enolate alkylation (SOMO activation)
Lecture 39 - Enantioselective alkylation with chiral PTC
Lecture 40 - Overall analysis of the entire discussion

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