NPTEL : NOC:One and two dimensional NMR Spectroscopy for Chemists (Chemistry and Biochemistry)

Co-ordinators : Prof. N. Suryaprakash


Lecture 1 - NMR an historical perspective and NMR active nuclei

Lecture 2 - Spin Angular Momentum and Magnetic moment

Lecture 3 - Interaction of Spins with the magnetic field

Lecture 4 - Larmor Precession and Energy of interaction

Lecture 5 - NMR detection and sensitivity

Lecture 6 - Inducing Resonance and Bulk Magnetization

Lecture 7 - Signal detection and Rotating Frame Concept

Lecture 8 - Pulse phase and signal phase

Lecture 9 - FID and Fourier Transformation

Lecture 10 - Selection rules and transitions

Lecture 11 - External and Internal interactions in NMR

Lecture 12 - Chemical Shifts

Lecture 13 - NMR Spectrum and chemical equivalence

Lecture 14 - Conversion of frequency and ppm

Lecture 15 - Field dependence and factors affecting chemical shift

Lecture 16 - Factors contributing to chemical shifts - 1

Lecture 17 - Factors contributing to chemical shifts - 2

Lecture 18 - Scalar Couplings - 1

Lecture 19 - Scalar Couplings - 2

Lecture 20 - Energy levels of coupled spins

Lecture 21 - Spin system classification and multiplicity

Lecture 22 - Multiplicity pattern of coupled spins

Lecture 23 - Active and passive coupling

Lecture 24 - Coupling among equivalent spins - 1

Lecture 25 - Coupling among equivalent spins - 2

Lecture 26 - Coupling among non-equivalent spins

Lecture 27 - Geminal and Vicinal couplings

Lecture 28 - Spin system Nomenclature

Lecture 29 - Isotope effect

Lecture 30 - Analysis of Strongly coupled spin systems

Lecture 31 - Eigen values of A2 and AMX spin systems

Lecture 32 - Analysis of Three spin coupled systems

Lecture 33 - Analysis of Proton NMR spectra - 1

Lecture 34 - Analysis of Proton NMR spectra - 2

Lecture 35 - Analysis of Proton NMR spectra - 3

Lecture 36 - Basics of 13C-NMR

Lecture 37 - Coupled and Decoupled 13C-Spectra

Lecture 38 - Broadband decoupling in 13C-NMR

Lecture 39 - Analysis of 13C spectra and DEPT

Lecture 40 - Heteronuclear couplings and satellite analysis - 1

Lecture 41 - Heteronuclear couplings and satellite analysis - 2

Lecture 42 - Coupling among magnetic equivalent nuclei and isotope effect

Lecture 43 - Analysis of spectra of other nuclei

Lecture 44 - Spin Echoes

Lecture 45 - Polarization transfer techniques

Lecture 46 - INEPT and DEPT

Lecture 47 - Decoupling and NOE

Lecture 48 - NOE-2

Lecture 49 - Introduction to 2D NMR

Lecture 50 - Two-dimensional NMR

Lecture 51 - Two dimensional NMR

Lecture 52 - Two dimensional COSY

Lecture 53 - COSY and examples

Lecture 54 - Variants of COSY and TOCSY spectra

Lecture 55 - Heteronuclear correlation and inverse detection

Lecture 56 - Coupled and decoupled HSQC and HMBC

Lecture 57 - NMR data acquisition - 1

Lecture 58 - NMR data acquisition - 2

Lecture 59 - Practical considerations of 1D NMR

Lecture 60 - NMR Data processing

Lecture 61 - NMR Data processing

Lecture 62 - NMR Instrumentation - 1

Lecture 63 - NMR Instrumentation - 2

Lecture 64 - Relaxation processes - 1

Lecture 65 - Relaxation processes - 2