NPTEL : NOC:Physics of Biological Systems (Physics)

Co-ordinators : Prof. Mithun Mitra


Lecture 1 - Introduction

Lecture 2 - DNA packing and structure

Lecture 3 - Shape and function

Lecture 4 - Numbers and sizes

Lecture 5 - Spatial scales and System variation

Lecture 6 - Timescales in Biology

Lecture 7 - Random walks and Passive diffusion

Lecture 8 - Random walks to model Biology

Lecture 9 - Derivation of FRAP equations

Lecture 10 - Drift-diffusion equations

Lecture 11 - Solutions of the drift-diffusion equations

Lecture 12 - The cell signaling problem

Lecture 13 - Cell Signalling and Capture Probability of absorbing sphere

Lecture 14 - Capture probability of reflecting sphere

Lecture 15 - Mean capture time

Lecture 16 - Introduction to fluids, viscosity and reynolds number

Lecture 17 - Introduction to the navier stokes equation

Lecture 18 - Understanding reynolds number

Lecture 19 - Life at low reynolds number

Lecture 20 - Various phenomena at low reynolds number

Lecture 21 - Bacterial flagellar motion

Lecture 22 - Rotating flagellum

Lecture 23 - Energy and equilibrium

Lecture 24 - Binding problems

Lecture 25 - Transcription and translation

Lecture 26 - Internal states of macromolecules

Lecture 27 - Protein modification problem

Lecture 28 - Haemoglobin-Oxygen binding problem

Lecture 29 - Freely jointed polymer model

Lecture 30 - Entropic springs and persistence length

Lecture 31 - Freely rotating chain model and radius of gyration

Lecture 32 - The hierarchical chromatin packing model

Lecture 33 - FISH and DNA looping

Lecture 34 - Nucleosomes as barriers, Hi-C, and contact probabilities

Lecture 35 - Deriving the full force extension curve

Lecture 36 - Random walk models for proteins

Lecture 37 - Hydrophobic polar protein model

Lecture 38 - Diffusion in crowded environments

Lecture 39 - Depletion interactions

Lecture 40 - Examples and implications of depletion interactions

Lecture 41 - Introduction to Biological dynamics

Lecture 42 - Introduction to rate equations

Lecture 43 - Separation of timescales in enzyme kinetics

Lecture 44 - Structure and treadmilling of actins and microtubules

Lecture 45 - Average length of polymers in equilibrium

Lecture 46 - Growth rate of polymers

Lecture 47 - Dynamic treadmilling in microtubules

Lecture 48 - Introduction to molecular motors

Lecture 49 - Force generation by molecular motors

Lecture 50 - Models of motor motion

Lecture 51 - molecular motors

Lecture 52 - Free energies of motor for stepping

Lecture 53 - Two state models

Lecture 54 - cooperative transport of cargo

Lecture 55 - Cytoskeleton as a motor

Lecture 56 - translocation ratchet

Lecture 57 - Spatial pattern in biology

Lecture 58 - Some common spatial patterns in biology

Lecture 59 - reaction diffusion and spatial pattern

Lecture 60 - Pattern formation in reaction diffusion system with stability

Lecture 61 - Condition for destablization in pattern formation

Lecture 62 - Schnakenberg kinetics