NPTEL : NOC:Essentials of Biomolecules: Nucleic Acids and Peptides (Chemistry and Biochemistry)

Co-ordinators : Prof. Lal Mohan Kundu


Lecture 1 - Importance of Biomolecules

Lecture 2 - DNA double helix: Chemical parameters

Lecture 3 - DNA and Proteins

Lecture 4 - Amino acids and Proteins

Lecture 5 - Protein 3D structures, folding and denaturation

Lecture 6 - Chemical synthesis pyrimidine nucleobases

Lecture 7 - Chemical synthesis purine nucleobases, Prebiotic chemistry

Lecture 8 - Synthesis of nucleosides

Lecture 9 - Solid phase DNA synthesis

Lecture 10 - Chemistry and Biology of DNA Replication

Lecture 11 - Chemistry of Polymerase Chain Reaction

Lecture 12 - Major components and steps involved in Polymerase chain reaction

Lecture 13 - DNA sequencing: Sanger's di-deoxy method

Lecture 14 - DNA sequencing: Maxam- Gilbert method

Lecture 15 - Numerical Problem-1

Lecture 16 - Sugar Chemistry

Lecture 17 - Chemistry behind DNA damage and mutation

Lecture 18 - Chemistry behind DNA damage and mutation

Lecture 19 - DNA repair

Lecture 20 - Transcription - The transfer of genetic information from DNA to mRNA

Lecture 21 - Translation - The transfer of genetic information from mRNA to protein I

Lecture 22 - Translation - The transfer of genetic information from mRNA to protein II

Lecture 23 - Role of Ribosome in protein synthesis and the concept of codon

Lecture 24 - Protein sequencing using Sanger's and Edman's degradation methods

Lecture 25 - Mass spectroscopy and other sequencing methods for large proteins

Lecture 26 - Solution phase peptide synthesis: mechanism and end protection

Lecture 27 - Peptide coupling agents, Solid phase synthesis, peptide based therapeutics

Lecture 28 - Spectroscopic techniques

Lecture 29 - Spectrospic techniques - II and Purification technique-I of biomolecules

Lecture 30 - Purification techniques - II and Characteriation techniques of biomolecules

Lecture 31 - Molecular probes: PNA and LNA-I

Lecture 32 - Molecular Probes: PNA and LNA-II

Lecture 33 - Carbohydrate chemistry - I: Introduction and Synthesis

Lecture 34 - Carbohydrate chemistry - II: Polysaccharides and its nanoparticles

Lecture 35 - Carbohydrate chemistry - III: Synthesis of nanoparticles; Recap of all modules