NPTEL : NOC:Medicinal Chemistry (Chemistry and Biochemistry)

Co-ordinators : Prof. Harinath Chakrapani


Lecture 1 - Introduction to Medicinal Chemistry - Part I

Lecture 2 - Introduction to Medicinal Chemistry - Part II

Lecture 3 - Intermolecular Binding Forces

Lecture 4 - Protein Structure and Function

Lecture 5 - Tutorial 1 - Acidity, Basicity and Related concepts

Lecture 6 - Tutorial 2 - Basic Concepts of Thermodynamics and Kinetics

Lecture 7 - Enzyme Catalysis - Part I

Lecture 8 - Enzyme Catalysis - Part II

Lecture 9 - Tutorial 3 - Binding Forces, Protein Structure and Function

Lecture 10 - Introduction to Receptors

Lecture 11 - Receptor Types and Functions

Lecture 12 - Tutorial 4 - Receptors, Binding Interactions, Ion Channels

Lecture 13 - Nucleic Acids

Lecture 14 - RNA and Protein Synthesis

Lecture 15 - Tutorial 5 - Nucleic acids, and Basics of Molecular Biology

Lecture 16 - Enzymes as Drug Targets

Lecture 17 - Enzyme Kinetics and Inhibition

Lecture 18 - Tutorial 6 - Enzyme Kinetics, Various Modes of Inhibition etc.

Lecture 19 - Receptors as Drug Targets - Part I

Lecture 20 - Receptors as Drug Targets - Part II

Lecture 21 - Tutorial 7 - Receptor-Drug Interactions, Stereochemistry, Chirality, Nomenclature

Lecture 22 - Receptor-Drug Interactions.

Lecture 23 - Stereochemistry and Conformation

Lecture 24 - Tutorial 8 - Determination of Drug-Receptor Interactions, Conformation of Cyclic and Acyclic Structures etc.

Lecture 25 - Nucleic Acids as Drug Targets - Part I

Lecture 26 - Nucleic Acids as Drug Targets - Part II

Lecture 27 - Miscellaneous Drug Targets

Lecture 28 - Tutorial 9 - Nucleic Acids and Related Topics

Lecture 29 - Mechanisms in Biological Chemistry - Part I

Lecture 30 - Mechanisms in Biological Chemistry - Part II

Lecture 31 - Mechanisms in Biological Chemistry - Part III

Lecture 32 - Pharmacokinetics - Part I

Lecture 33 - Pharmacokinetics - Part II

Lecture 34 - Drug Metabolism - Part I

Lecture 35 - Drug Metabolism - Part II

Lecture 36 - Drug Metabolism - Part III

Lecture 37 - Drug Metabolism - Part IV

Lecture 38 - Tutorial 10 - ADME

Lecture 39 - Drug Administration Routes - Part I

Lecture 40 - Drug Administration Routes - Part II

Lecture 41 - Finding a Lead - Part I

Lecture 42 - Finding a Lead - Part II

Lecture 43 - Drug Screening

Lecture 44 - Tutorial 11 - Drug administration routes and finding a lead

Lecture 45 - Optimizing Drug-Target Interactions - Part I

Lecture 46 - Optimizing Drug-Target Interactions - Part II

Lecture 47 - Optimizing Drug-Target Interactions - Part III

Lecture 48 - Optimizing Drug-Target Interactions - Part IV

Lecture 49 - Tutorial 12

Lecture 50 - Optimizing Access to the Target

Lecture 51 - Prodrugs

Lecture 52 - Prodrugs and Drug Alliances

Lecture 53 - Endogenous Compounds, Peptidomimetics and Oligonucleotides as Drugs

Lecture 54 - Tutorial 13- Optimizing Access-Prodrugs

Lecture 55 - Combinatorial and parallel synthesis

Lecture 56 - Computer in Medicinal Chemistry

Lecture 57 - Antibacterial agents - 1

Lecture 58 - Antibacterial agents - 2

Lecture 59 - Tutorial14-Combinatorial and parallel synthesis, computers in med chem and anti-bacterial agents

Lecture 60 - Anti-viral agents - 1

Lecture 61 - Anti-viral agents - 2

Lecture 62 - Anti-cancer agents - 1

Lecture 63 - Anti-cancer agents - 2

Lecture 64 - Cholinergics

Lecture 65 - Anti-ulcer agents

Lecture 66 - QSAR - 1

Lecture 67 - QSAR - 2

Lecture 68 - QSAR - 3

Lecture 69 - Drug Resistance and Synergy