NPTEL : NOC:Metals in Biology (Chemistry and Biochemistry)

Co-ordinators : Prof.Debabrata Maiti


Lecture 1 - Importance of metals in biology

Lecture 2 - Choice, uptake and assembly of metal ions in cells

Lecture 3 - Control and use of metal ions concentration in biological systems

Lecture 4 - Metal mediated folding of biopolymers

Lecture 5 - Study of binding mode of calcium and zinc in proteins

Lecture 6 - Electron transfer (ET) in living systems

Lecture 7 - Oxygen transport and activation

Lecture 8 - Hydrolytic Enzymes - Part I - Carbonic anhydrase and Liver alcohol dehydrogenase

Lecture 9 - Hydrolytic Enzymes - Part II - Carbopeptidase

Lecture 10 - Hydrolytic Enzymes - Part III - Arginase and Urease

Lecture 11 - Hemerythrin and azidomethemerythrin

Lecture 12 - Dioxygen reactivity in copper

Lecture 13 - Cu-O2 intermediates

Lecture 14 - Copper-Oxygen chemistry - Part I - Mononuclear copper-oxygen

Lecture 15 - Copper-Oxygen chemistry - Part II - Cu-O2 complexes

Lecture 16 - Copper-Oxygen chemistry - Part III - Reactivity summary

Lecture 17 - Iron Catalyzed oxidation of unactivated sp3 C-H bonds - Part I

Lecture 18 - Iron catalyzed oxidation of unactivated sp3 C-H bonds - Part II

Lecture 19 - Iron catalyzed oxidation of unactivated sp3 C-H bonds - Part III

Lecture 20 - Nitrous oxide reductase and its model complex

Lecture 21 - Cytochrome C-oxidase

Lecture 22 - Systematic variations in O-O stretch in Iron-oxo-copper ligand complex

Lecture 23 - Mononuclear nonheme iron (NHI) enzymes

Lecture 24 - Alpha-Keto Glutarate dependent Halogenases

Lecture 25 - Cytochrome P450 - Part I - Introduction

Lecture 26 - Cytochrome P450 - Part II - Reactions

Lecture 27 - Cytochrome P450 - Part III - Mechanism

Lecture 28 - Cytochrome P450 - Part IV - Role of Cystine ligand and distal charge relay

Lecture 29 - Methane monooxygenase

Lecture 30 - Dinuclear Iron active sites for CH4 to CH4OH conversion and its Mechanism

Lecture 31 - Concerted Vs radical pathway for CH4 to CH4OH conversion

Lecture 32 - Photosynthesis - Part I

Lecture 33 - Photosynthesis - Part II

Lecture 34 - Pumps and channels

Lecture 35 - Quick summary on O2 transport

Lecture 36 - Summary of Dioxygen reactivity in copper

Lecture 37 - Summary of Dioxygen reactivity in iron

Lecture 38 - Summary of Fe-O2 chemistry