NPTEL : NOC:Algorithms for Protein Modelling and Engineering (Computer Science and Engineering)

Co-ordinators : Prof. Pralay Mitra


Lecture 1 - Introduction on Proteins

Lecture 2 - Introduction on Proteins (Continued...) and Sequence Database

Lecture 3 - Protein Data Bank

Lecture 4 - PDB Parsing

Lecture 5 - Molecular Visualization Tools

Lecture 6 - Representation and Data Structure

Lecture 7 - Digitization of a Molecule

Lecture 8 - Application to Protein Docking, FFT

Lecture 9 - Implementation Details

Lecture 10 - Hashing

Lecture 11 - Geometric Hashing

Lecture 12 - Geometric Hashing (Continued...)

Lecture 13 - Geometric Hashing (Continued...)

Lecture 14 - Molecular Surface

Lecture 15 - Genetic Algorithm (GA) for Surface Comparison

Lecture 16 - Monte Carlo (MC) Method

Lecture 17 - Monte Carlo Method (Continued...) and Random Number

Lecture 18 - Monte Carlo (MC) Method (Continued...)

Lecture 19 - Protein Folding

Lecture 20 - Protein Folding (Continued...) and Protein Design

Lecture 21 - Protein Energy Landscape

Lecture 22 - Protein Energy Landscape (Continued...), Limitation of MC

Lecture 23 - Replica Exchange Monte Carlo (REMC)

Lecture 24 - Ab Initio Protein Folding

Lecture 25 - Structure Alignment Measures

Lecture 26 - Dynamic Programming

Lecture 27 - Dynamic Programming (Continued...), Sequence Alignment

Lecture 28 - Dynamic Programming (Continued...), Position Specific Scoring Matrix (PSSM)

Lecture 29 - Structure Alignment

Lecture 30 - Structure Alignment (Continued...)

Lecture 31 - Structural Classification of Proteins (SCOP)

Lecture 32 - SCOP (Continued...), Symmetry in Proteins

Lecture 33 - Symmetry in Proteins

Lecture 34 - Discriminating Biological Protein Interfaces from Crystal Artifacts

Lecture 35 - Discriminating Biological Protein Interfaces from Crystal Artifacts (Continued...)

Lecture 36 - Discriminating Biological Protein Interfaces from Crystal Artifacts (Continued...)

Lecture 37 - Discriminating Biological Protein Interfaces from Crystal Artifacts (Continued...)

Lecture 38 - Symmetry-Based Protein Complex Modeling

Lecture 39 - Some Protein Docking Methods

Lecture 40 - Some Protein Docking Methods (Continued...)

Lecture 41 - Computational Protein Design (CPD)

Lecture 42 - Computational Protein Design (CPD) (Continued...)

Lecture 43 - Protein Design Energy Function

Lecture 44 - Protein Design Analysis

Lecture 45 - Application of Protein Design on Drug Design

Lecture 46 - RECM in Protein Design

Lecture 47 - Application of Protein Design on Drug Design

Lecture 48 - Application of Protein Design on Drug Design (Continued...), Protein Modification

Lecture 49 - Protein Modification (Continued...)

Lecture 50 - Protein Modification (Continued...)

Lecture 51 - Assigning Secondary Structure to Protein Sequence

Lecture 52 - Assigning Secondary Structure to Protein Sequence (Continued...)

Lecture 53 - Machine Learning to Predict the Secondary Structure from Amino Acid Sequences

Lecture 54 - Machine Learning to Predict the Secondary Structure from Amino Acid Sequences (Continued...)

Lecture 55 - Post Translational Modification

Lecture 56 - Predicting Protein Phosphorylation Sites

Lecture 57 - Predicting Protein Phosphorylation Sites (Continued...)

Lecture 58 - Summarizing Protein Folding and Protein Docking

Lecture 59 - Summarizing Protein Folding and Protein Docking (Continued...)

Lecture 60 - Summarizing Potein Engineering