NPTEL : NOC:Introduction to Mechanobiology (Biotechnology)

Co-ordinators : Prof. Shamik Sen


Lecture 1 - Need to Study Mechanobiology

Lecture 2 - Cell as a Tent, Individual Components

Lecture 3 - Cell-ECM Crosstalk

Lecture 4 - ECM Proteins: Collagen

Lecture 5 - Measuring Properties of Collagen Networks

Lecture 6 - Properties of Collagen Networks

Lecture 7 - Rheology

Lecture 8 - Rheology of Biopolymer Networks

Lecture 9 - Atomic Force Microscopy (AFM)

Lecture 10 - Design of Protein Constructs for AFM

Lecture 11 - Protein Unfolding using AFM

Lecture 12 - Protein Unfolding using AFM

Lecture 13 - Focal Adhesions: Focal Adhesion Proteins

Lecture 14 - Focal Adhesion Organization

Lecture 15 - Focal Adhesions: Role of Forces

Lecture 16 - Cytoskeleton: Actin

Lecture 17 - Force-velocity Relationships of Actin Networks

Lecture 18 - Mesenchymal Cell Migration

Lecture 19 - Actin Dynamics during Mesenchymal Migration

Lecture 20 - Actin Dynamics during Mesenchymal Migration

Lecture 21 - Adhesion Independent Migration

Lecture 22 - Adhesion Independent and Collective Cell Migration

Lecture 23 - Collective Cell Migration

Lecture 24 - Mechanobiology of Stem Cell Fate - I

Lecture 25 - Mechanobiology of Stem Cell Fate - II

Lecture 26 - Mechanobiology of Stem Cell Fate - III

Lecture 27 - Mechanobiology of Diseases: Cancer - I

Lecture 28 - Mechanobiology of Diseases: Cancer - II

Lecture 29 - Mechanobiology of Diseases: Cancer - III

Lecture 30 - Mechanobiology of Diseases: Atherosclerosis and Hypertension

Lecture 31 - Mechanobiology of Diseases: Muscular Dystrophy

Lecture 32 - Nuclear Mechanotransduction: LINC complex

Lecture 33 - Nuclear Mechanotransduction: LINC Complex in Cell Migration

Lecture 34 - Nuclear Mechanotransduction: Gene Regulation

Lecture 35 - Mechanical Forces and DNA damage

Lecture 36 - Techniques in Mechanobiology: Hydrogels

Lecture 37 - Techniques in Mechanobiology: AFM

Lecture 38 - Techniques in Mechanobiology: Traction Force Microscopy, Trypson Deadhesion and Laser Ablation

Lecture 39 - Techniques in Mechanobiology: Microfabrication

Lecture 40 - Techniques in Mechanobiology: FRET