NPTEL : NOC:NMR Spectroscopy for Chemists and Biologists (Chemistry and Biochemistry)

Co-ordinators : Prof. Ashutosh Kumar


Lecture 1 - Basic concepts

Lecture 2 - Resonance absorption

Lecture 3 - Bloch Equations

Lecture 4 - Relaxation

Lecture 5 - Introduction to Chemical Shift

Lecture 6 - Factors affecting Isotropic Chemical Shifts

Lecture 7 - Spin-Spin Coupling

Lecture 8 - Interpretation of multiplet structure using first order analysis

Lecture 9 - Analysis of NMR spectra of molecules

Lecture 10 - Quantum Mechanical Analysis - Part I

Lecture 11 - Quantum Mechanical Analysis - Part II

Lecture 12 - Dynamic effects in the NMR Spectra

Lecture 13 - Fourier Transform NMR

Lecture 14 - Theorems on Fourier Transform

Lecture 15 - Practical aspects of Fourier Transform NMR spectra

Lecture 16 - Data Processing in Fourier Transform NMR

Lecture 17 - Dynamic range in Fourier Transform NMR

Lecture 18 - Spin Echo and Solvent Suppression

Lecture 19 - Spin Decoupling in FT NMR and Relaxation Measurements

Lecture 20 - Polarization Transfer

Lecture 21 - Nuclear Overhauser Effect

Lecture 22 - Steady state NOE and Transient NOE

Lecture 23 - Distance and NOE

Lecture 24 - Selective Population Inversion

Lecture 25 - INEPT and Sensitivity Enhancement

Lecture 26 - Rotating Frame Experiments

Lecture 27 - Density matrix description of NMR - I

Lecture 28 - Density matrix description of NMR - II

Lecture 29 - Density matrix description of NMR - III

Lecture 30 - Time evolution of density operator

Lecture 31 - Density matrix description of NMR - IV

Lecture 32 - Evolution of density operator in the presence of RF

Lecture 33 - Product operator formalism

Lecture 34 - Product operator formalism (Continued...)

Lecture 35 - Product operator formalism (Continued...)

Lecture 36 - Time evolution of basis operators

Lecture 37 - Observable and Non-observable basis operators, Spin echo

Lecture 38 - Spin echo (Continued...)

Lecture 39 - INEPT

Lecture 40 - Multidimensional NMR Spectroscopy

Lecture 41 - Two Dimensional NMR - Part I

Lecture 42 - Two Dimensional NMR - Part II

Lecture 43 - Types of 2D NMR Spectra

Lecture 44 - Two Dimensional Separation of Interaction in NMR

Lecture 45 - Two Dimensional Correlation Experiments - I

Lecture 46 - Two Dimensional Correlation Experiments - II

Lecture 47 - Two Dimensional Correlation Experiments - III

Lecture 48 - Double Quantum Filtered COSY (DQF-COSY)

Lecture 49 - Two Dimensional Nuclear Overhauser Effect Spectroscopy (2D- NOESY)

Lecture 50 - Constant-time COSY

Lecture 51 - Scaling in 2D NMR

Lecture 52 - Total Correlation Spectroscopy

Lecture 53 - 2D Heteronuclear Experiment - I

Lecture 54 - 2D Heteronuclear Experiment - II

Lecture 55 - Multidimensional NMR

Lecture 56 - Structure Determination of Peptides by NMR - I

Lecture 57 - Structure Determination of Peptides by NMR - II

Lecture 58 - Protein-Ligand Interaction - I

Lecture 59 - Protein-Ligand Interaction - II

Lecture 60 - Diffusion Ordered Spectroscopy